X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining.

doi:10.1016/0167-8817(84)90037-3

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Article

X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining.

Mutation research - 1 Jan 2000

Kemp L M, Sedgwick S G, Jeggo P A

Abstract excerpt

Six CHO mutants have previously been described as being sensitive to ionizing radiation and bleomycin treatment, with little or no cross sensitivity to UV-radiation (Jeggo and Kemp, 1983). Their ability to rejoin single- and double-strand breaks has been examined here. Using two techniques, gradi...

Topics

Animals
Cell Line
Cricetinae
Cricetulus
DNA Repair
DNA, Single-Stranded
Female
Kinetics
Mutation
Ovary
Ultraviolet Rays
X-Rays

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