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Article

Functional expression of human P-glycoprotein in Schizosaccharomyces pombe.

FEBS letters - 20 Sept 1993

Ueda K, Shimabuku A M, Konishi H, Fujii Y, Takebe S, Nishi K, Yoshida M, Beppu T, Komano T

Abstract excerpt

Human MDR1 cDNA was introduced into the human cultured cells KB-3-1 and Schizosaccharomyces pombe pmd1 null mutant KN3. The drug sensitivity of KB-G2 and KN3/pgp, expressing human P-glycoprotein, was examined. KB-G2 was resistant to the peptide antibiotics valinomycin and gramicidin D as well as having a typical multidrug resistance (MDR) phenotype. KN3/pgp was resistant to valinomycin and actinomycin D, but not...

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PMID: 7690715
DOI: 10.1016/0014-5793(93)80888-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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