Article
Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe.
Journal of virology - 1 Sept 1996
Zhao Y, Cao J, O'Gorman M R, Yu M, Yogev R
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) Vpr protein affects cell morphology and prevents proliferation of human cells by induction of cell cycle G2 arrest. In this study, we used the fission yeast Schizosaccharomyces pombe as a model system to investigate the cellular effects of HIV-1 vpr...
Topics
- CDC2 Protein Kinase
- Cell Cycle
- Cell Division
- Cloning, Molecular
- G2 Phase
- Gene Products, vpr
- Genes, vpr
- HIV-1
- Humans
- Kinetics
- Phenotype
- Phosphorylation
- Schizosaccharomyces
- Time Factors
- vpr Gene Products, Human Immunodeficiency Virus