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Article

Drug-stimulated ATPase activity of a deletion mutant of the human multidrug-resistance protein (MDR1).

Biochemical and biophysical research communications - 13 Nov 1995

Welker E, Szabó K, Holló Z, Müller M, Sarkadi B, Váradi A

Abstract excerpt

The baculovirus-insect cell system has been used for the functional expression of the human multidrug resistance protein (MDR1) and a mutant MDR1 variant lacking a twenty amino acid segment from the first extracellular loop (delta aa78-97 MDR1). Both MDR1 proteins were found to be correctly inserted into the insect cell membrane as indicated by their interaction with MRK 16 antibody. The removal of the 78-97...

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Identifiers

PMID: 7488154
DOI: 10.1006/bbrc.1995.2665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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