Article
Two truncated forms of rat insulin receptor-related receptor.
The Journal of biological chemistry - 25 Aug 1993
Itoh N, Jobo K, Tsujimoto K, Ohta M, Kawasaki T
Abstract excerpt
The insulin receptor-related receptor (IRR) (1271 amino acids) is expected to have unique functions as a novel member of the insulin receptor family. In this paper, we report two alternatively spliced variants of rat IRR mRNA, which are predicted to encode two truncated forms of IRR, sIRR-1 (410 amino acids) and sIRR-2 (469 amino acids). The amino acid sequence of sIRR-1 is identical to the N-terminal 410-amino...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Western
- Exons
- Gastric Mucosa
- Genetic Variation
- Introns
- Kidney
- Molecular Sequence Data
- Molecular Weight