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Article

mRNA and Protein Expression of Fetal Insulin Receptor in Breast Cancer Cell Lines

2025-12-17

Abstract excerpt

The insulin receptor (IR) is expressed in breast cancer cells and plays a role in regulating tumor biology. There are two IR isoforms generated from the same gene. Alternate splicing with exclusion or inclusion of exon 11accounts for the two isoforms. The exon 11 excluded isoform (IR-A) is expressed during fetal development while the full-length adult IR (IR-B) is the primary form expressed during adult life. This...

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Identifiers and source

Literature Corpus work
d535beba-1f7e-51e3-8764-15c5bb814d40
DOI
10.64898/2025.12.15.694420
Open publication

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