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Article

Genotoxic potential of psoralen cross-links versus monoadducts in normal human lymphoblasts.

Mutation research - 1 Mar 1995

Laquerbe A, Moustacchi E, Papadopoulo D

Abstract excerpt

Using the 4,5',8-trimethylpsoralen in combination with the reirradiation protocol, we show that, in normal human lymphoblasts, the cytotoxic potential of photoinduced cross-links (CL) is higher than that of monoadducts (MA). In contrast to cytotoxicity, the significant increase in the proportion of CL, at a constant level of total adducts, had no effect on the induction of mutations at the HPRT locus. Comparison...

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Source

Identifiers

PMID: 7700281
DOI: 10.1016/0165-7992(95)90050-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genotoxic potential of psoralen cross-links versus monoadducts in normal human lymphoblasts.PMID 7700281Read ↗

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