Article
Functional role of the cytoplasmic domain of the integrin alpha 5 subunit.
The Journal of cell biology - 1 Jul 1993
Bauer J S, Varner J, Schreiner C, Kornberg L, Nicholas R, Juliano R L
Abstract excerpt
The purpose of this study was to explore the functional role of the cytoplasmic domain of the alpha subunit of the alpha 5/beta 1 integrin, a fibronectin receptor. Mutant CHO cells that express very low levels of endogenous hamster alpha 5 subunit (CHO clone B2) were transfected with an expression vector containing full-length or truncated human alpha 5 cDNAs to form chimeric human alpha 5/hamster beta 1...
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