Article
beta1-integrin cytoplasmic subdomains involved in dominant negative function.
Molecular biology of the cell - 1 Apr 1998
Retta S F, Balzac F, Ferraris P, Belkin A M, Fässler R, Humphries M J, De Leo G, Silengo L, Tarone G
Abstract excerpt
The beta1-integrin cytoplasmic domain consists of a membrane proximal subdomain common to the four known isoforms ("common" region) and a distal subdomain specific for each isoform ("variable" region). To investigate in detail the role of these subdomains in integrin-dependent cellular functions,...
Topics
- Actinin
- Amino Acid Sequence
- Animals
- Antigens, CD
- Binding Sites
- CHO Cells
- Cell Adhesion
- Cell Adhesion Molecules
- Cricetinae
- Cytoplasm
- Fibronectins
- Focal Adhesion Kinase 1
- Focal Adhesion Protein-Tyrosine Kinases
- Integrin alpha5
- Integrin alphaV
- Integrin beta1
- Integrin beta3
- Mice