Article
Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages.
Molecular biology of the cell - 1 Jun 1994
Shaw L M, Mercurio A M
Abstract excerpt
Several integrin alpha subunits have structural variants that are identical in their extracellular and transmembrane domains but that differ in their cytoplasmic domains. The functional significance of these variants, however, is unknown. In the present study, we examined the possibility that the...
Topics
- Animals
- Calcium
- Cell Adhesion
- Cell Communication
- Cell Line
- Cell Movement
- Cytoplasm
- DNA, Complementary
- Genetic Variation
- Integrin alpha6beta1
- Integrins
- Laminin
- Macrophages
- Manganese
- Mice