Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure and function of C-CAM1. The first immunoglobulin domain is required for intercellular adhesion.

The Journal of biological chemistry - 15 Nov 1993

Cheung P H, Luo W, Qiu Y, Zhang X, Earley K, Millirons P, Lin S H

Abstract excerpt

Cell-CAM105 proteins (also called C-CAM) are epithelial cell adhesion molecules of the immunoglobulin (Ig) superfamily. The sequences of C-CAM are highly homologous to those of human carcinoembryonic antigen (CEA)-family proteins. In previous studies using baculoviral vectors, we showed that expression of the L-form cell-CAM105 (also called C-CAM1) in insect cells resulted in cell aggregation (Cheung, P. H.,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Base Sequence
Share to Calcium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line

Share to DNA, Complementary

Share to Molecular Sequence Data

Share to Mutation

Share to Sequence Deletion

Source

Identifiers

PMID: 8226979

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure and function of C-CAM1. The first immunoglobulin domain is required for intercellular adhesion.PMID 8226979Read ↗

Pathogenic human L1-CAM mutations reduce the adhesion-dependent activation of EGFR.Semantic proximity Read ↗

A conserved role for L1 as a transmembrane link between neuronal adhesion and membrane cytoskeleton assembly.Semantic proximity Read ↗

Homophilic intercellular adhesion mediated by C-CAM is due to a domain 1-domain 1 reciprocal binding.Semantic proximity Read ↗

Calmodulin binds to specific sequences in the cytoplasmic domain of C-CAM and down-regulates C-CAM self-association.Semantic proximity Read ↗

Functional role of the cytoplasmic domain of the integrin alpha 5 subunit.Semantic proximity Read ↗

The role of cell adhesion molecule in cancer progression and its application in cancer therapy.Semantic proximity Read ↗

The L1 family of neural cell adhesion molecules: old proteins performing new tricks.Semantic proximity Read ↗

Characterization of cDNA clones defining variant forms of human neural cell adhesion molecule N-CAM.Semantic proximity Read ↗

[Cell adhesion proteins in the nervous system: immunoglobulin superfamily--structure, function and involvement in neurological diseases].Semantic proximity Read ↗

Expression and function of calcium binding domain chimeras of the integrins alpha(IIb) and alpha(5).Semantic proximity Read ↗

Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoformsSemantic proximity Read ↗

Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.