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Article

Functional analysis of the cytoplasmic domain of the integrin {alpha}1 subunit in endothelial cells.

Blood - 15 Oct 2008

Abair Tristin D, Bulus Nada, Borza Corina, Sundaramoorthy Munirathinam, Zent Roy, Pozzi Ambra

Abstract excerpt

Integrin alpha1beta1, the major collagen type IV receptor, is expressed by endothelial cells and plays a role in both physiologic and pathologic angiogenesis. Because the molecular mechanisms whereby this collagen IV receptor mediates endothelial cell functions are poorly understood, truncation and point mutants of the integrin alpha1 subunit cytoplasmic tail (amino acids 1137-1151) were generated and expressed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18647959
DOI: 10.1182/blood-2007-12-126433
PMCID: PMC2569176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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