Article
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
Carcinogenesis - 1 Nov 1993
Hennings H, Glick A B, Lowry D T, Krsmanovic L S, Sly L M, Yuspa S H
Abstract excerpt
The widespread use of FVB/N mice for the establishment of transgenic lines containing active oncogenes suggested the importance of testing the parent FVB/N mice for sensitivity to experimental carcinogenesis. After initiation of mouse skin by a single treatment with 7,12-dimethylbenz[a]anthracene...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Acetone
- Animals
- Carcinoma, Squamous Cell
- Drug Resistance
- Female
- Genetic Predisposition to Disease
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Papilloma
- Skin Neoplasms
- Species Specificity
- Tetradecanoylphorbol Acetate