Article
Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er).
International journal of cancer - 15 Nov 1990
Reddy A L, Fialkow P J
Abstract excerpt
Mice heterozygous for repeated epilation mutation (Er) have cutaneous abnormalities that result in repeated loss of hair. Skin papillomas and carcinomas occur spontaneously in such Er/+ mice. BALB/c mice are generally resistant to induced skin cancers. We investigated whether Er/+ heterozygous mi...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Female
- Hair Removal
- Heterozygote
- Male
- Mice
- Mice, Inbred BALB C
- Mutation
- Papilloma
- Skin Neoplasms
- Tetradecanoylphorbol Acetate