Article
Analysis of the B-cell compartment in plasma cell leukemia and multiple myeloma: immunoglobulin gene rearrangement of EBV-infected B-cell lines.
Leukemia - 1 Apr 1993
Commes T, Clofent G, Ghanem N, Zhang X G, Lefranc M P, Bataille R, Klein B
Abstract excerpt
Multiple myeloma (MM) is defined as a tumoral expansion of plasma cells occurring in the bone marrow and sometimes in the peripheral blood (plasma-cell leukemia, PCL). Many reports have demonstrated a clonal expansion of B cells bearing the same idiotypic determinants as the myeloma protein (idio...
Topics
- Antigens, CD
- Antigens, CD20
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Blotting, Southern
- Bone Marrow
- Cell Transformation, Viral
- Clone Cells
- Gene Rearrangement
- Herpesvirus 4, Human
- Humans
