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Article

Ig gene sequences in the study of clonality.

Pathologie-biologie - 1 Feb 1999

Bakkus M H

Abstract excerpt

Investigations of normal and neoplastic B cells are being channelled into new directions by recent work on immunoglobulin variable region genes. Assembling of heavy and light chain genes introduces enormous heterogeneity into the third complementarity determining regions (CDR3s) of immunoglobulins. For reasons that will become apparent below, variation in CDR3s is especially broad in heavy chains. Moreover,...

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PMID: 10192880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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