Article
Circulating clonotypic B cells in multiple myeloma and monoclonal gammopathy of undetermined significance
19 Jul 2013
Abstract excerpt
The B-cell compartment in which multiple myeloma stem cells reside remains unclear. We investigated the potential presence of mature, surface-membrane immunoglobulin-positive B lymphocytes clonally related to the tumor bone marrow plasma cells among different subsets of peripheral blood B cells from ten patients (7 with multiple myeloma and 3 with monoclonal gammopathies of undetermined significance). The...
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