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Article

The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase.

The Journal of biological chemistry - 25 Mar 1993

Pullen K A, Rattray A J, Champoux J J

Abstract excerpt

A specific cleavage by the reverse transcriptase-associated RNase H activity generates the RNA primer for plus strand DNA synthesis during reverse transcription. Previously, we used site-directed mutagenesis to define the sequence features of the polypurine tract (PPT) required for correct plus strand priming by the Moloney murine leukemia virus (M-MuLV) reverse transcriptase (Rattray, A. J., and Champoux, J. J....

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Source

Identifiers

PMID: 7681062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase.PMID 7681062Read ↗

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Processing of the primer for plus strand DNA synthesis by human immunodeficiency virus 1 reverse transcriptase.Semantic proximity Read ↗

Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptase.Semantic proximity Read ↗

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Mutations within the primer binding site of the human immunodeficiency virus type 1 define sequence requirements essential for reverse transcription.Semantic proximity Read ↗

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