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Article

Mutational Status of Codons 12 and 13 of the N- andK-rasGenes in Tissue and Cell Lines Derived from Primary and Metastatic Prostate Carcinomas

1 Jan 1993

Abstract excerpt

N- and K-ras mutations at codons 12 and 13 were investigated using oligonucleotide hybridization analysis after PCR amplification and subsequent sequence analysis of the amplified DNA from the region of interest in the following prostatic primary and metastatic (met) carcinoma-derived cell lines: 1013L (primary), PC3 (bone met), DU145 (brain met), and LNCaP (lymph node met). We also examined fresh and archival...

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Identifiers

PMID: 7678540
DOI: 10.3109/07357909309020257

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