Article
Infrequent RAS oncogene mutations in human prostate cancer.
The Prostate - 1 Jan 1992
Moul J W, Friedrichs P A, Lance R S, Theune S M, Chang E H
Abstract excerpt
The RAS gene family includes three functional genes, H-RAS, K-RAS, and N-RAS, which have been most widely studied in human tumors. Point mutations most commonly occurring at codons 12, 13, or 61 of these genes allow the RAS protooncogene to be converted to a RAS oncogene. A variety of human tumor...
Topics
- Amino Acid Sequence
- Base Sequence
- Codon
- Cohort Studies
- Genes, ras
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Prostatic Neoplasms
- United States