Concurrent mutations of coding and regulatory sequences of the Ha-ras gene in urinary bladder carcinomas.

doi:10.1016/0046-8177(92)90285-b

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Article

Concurrent mutations of coding and regulatory sequences of the Ha-ras gene in urinary bladder carcinomas.

Human pathology - 1 Nov 1992

Czerniak B, Cohen G L, Etkind P, Deitch D, Simmons H, Herz F, Koss L G

Abstract excerpt

This report concerns the study of Ha-ras gene mutations and ras p21 expression in primary tumors of the urinary bladder. Polymerase chain reaction-based techniques and computerized image analysis were used. The data obtained were related to tumor grade, DNA ploidy, and tumor invasion. A point mut...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Codon
DNA Mutational Analysis
DNA, Neoplasm
Exons
Female
Gene Expression
Genes, ras
Humans
Introns
Male
Middle Aged
Molecular Sequence Data
Mutation
Neoplasm Invasiveness

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