Article
Comparison of ras activation in prostate carcinoma in Japanese and American men.
The Prostate - 1 Jan 1997
Konishi N, Hiasa Y, Tsuzuki T, Tao M, Enomoto T, Miller G J
Abstract excerpt
BACKGROUND: Comparative studies of point mutations in K-, N-, and H-ras oncogenes were performed on prostate carcinoma from Japanese and American patients to clarify the racial difference. METHODS: We probed for mutations in 70 Japanese and 31 American specimens using polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis and immunohistochemistry for ras p21. RESULTS: Within the 70...
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