Article
Detection of RAS mutations in archival testicular germ cell tumors by polymerase chain reaction and oligonucleotide hybridization.
Genes, chromosomes & cancer - 1 Sept 1992
Moul J W, Theune S M, Chang E H
Abstract excerpt
Preliminary studies of RAS mutational activation in human testicular germ cell neoplasms have yielded conflicting results. Whereas two studies of clinical material revealed a significant incidence of N- and KRAS mutations, two studies of a variety of germ cell lines failed to document RAS mutations. To clarify the incidence of RAS mutations in these tumors, we studied archival paraffin-embedded, formalin-fixed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
