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Article

BRAF and KRAS mutations in prostatic adenocarcinoma.

International journal of cancer - 15 Oct 2006

Cho Nam-Yun, Choi Minhee, Kim Baek-Hee, Cho Yong-Mee, Moon Kyung Chul, Kang Gyeong Hoon

Abstract excerpt

Constitutive activation of the kinase cascade involving RAS, RAF, MEK and ERK is common to human cancers, and mutations of KRAS and BRAF are mutually exclusive and serve as alternatives to activate the RAS/RAF/ERK signaling pathway. RAS mutations are known to occur in prostate adenocarcinomas, but little is known about BRAF mutations in these tumors. In the present study, BRAF and KRAS mutations were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16721785
DOI: 10.1002/ijc.22071

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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