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Article

Low frequency of mutations in the WT1 coding region in Wilms' tumor.

Genes, chromosomes & cancer - 1 Oct 1993

Brown K W, Wilmore H P, Watson J E, Mott M G, Berry P J, Maitland N J

Abstract excerpt

A series of twenty unselected Wilms' tumors were analysed for alterations in the WT1 tumor suppressor gene. The entire coding region of WT1 was amplified by RNA-PCR, and then screened for mutations by single-strand conformational polymorphism analysis (SSCP). This method was shown to be capable of detecting point mutations in the WT1 gene, by using an experimentally produced mutation. A single mutation, a 226 bp...

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Identifiers

PMID: 7504520
DOI: 10.1002/gcc.2870080203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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