Article
SCL/Tal-1 expression in T-acute lymphoblastic leukemia: an immunohistochemical and genotypic study.
Human pathology - 1 Sept 1995
Chetty R, Pulford K, Jones M, Mathieu-Mahul D, Close P, Hussein S, Pallesen G, Ralfkiaer E, Stein H, Gatter K
Abstract excerpt
A comparative study of the immunohistochemical (Stem cell leukemia/T-cell acute leukemia [SCL/TAL-1] protein expression) and genotypic (deletions in the SCL/tal-1 gene) findings in T-acute lymphoblastic leukemia (T-ALL) is presented. Formalin-fixed tissue from 50 cases of T-ALL were stained with...
Topics
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors
- DNA-Binding Proteins
- Gene Deletion
- Genotype
- Humans
- Immunohistochemistry
- Leukemia-Lymphoma, Adult T-Cell
- Molecular Probes
- Molecular Sequence Data
- Polymerase Chain Reaction