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Article

DNA synthesis errors associated with double-strand-break repair.

Genetics - 1 Jul 1995

Strathern J N, Shafer B K, McGill C B

Abstract excerpt

Repair of a site-specific double-strand DNA break (DSB) resulted in increased reversion frequency for a nearby allele. Site-specific DSBs were introduced into the genome of Saccharomyces cerevisiae by the endonuclease encoded by the HO gene. Expression of the HO gene from a galactose-inducible pr...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Chromosomes, Fungal
Crosses, Genetic
Crossing Over, Genetic
DNA Repair
DNA, Fungal
DNA-Directed DNA Polymerase
Diploidy
Frameshift Mutation
Genes, Fungal
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haploidy

Molecular Sequence Data

Mutagenesis

Oligodeoxyribonucleotides

Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 7672595
DOI: 10.1093/genetics/140.3.965
PMCID: PMC1206680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7672595-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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