Article
Recombination between genes located on nonhomologous chromosomes in Saccharomyces cerevisiae.
Genetics - 1 Jan 2000
Mikus M D, Petes T D
Abstract excerpt
We constructed strains of Saccharomyces cerevisiae that contained two different mutant alleles of either the leu2 gene or the ura3 gene. These repeated genes were located on chromosomes V and XII and the two leu2- alleles were located on chromosomes III and XII. Genetic interactions between the two mutant copies of a gene were detected by the generation of either Leu+ or Ura+ revertants. Both spontaneous and...
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