Article
Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks.
Nature - 17 Oct 1996
Moore J K, Haber J E
Abstract excerpt
Non-homologous repair of broken chromosomes in Saccharomyces cerevisiae can be studied at a defined location by expressing the site-specific HO endonuclease that cuts the mating-type (MAT) locus. When homologous recombination is prevented, most double-strand breaks are repaired by non-homologous end-joinings similar to those observed in mammalian cells. About 1% of non-homologous repair events were exceptional,...
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