Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks.

doi:10.1038/383644a0

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Article

Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks.

Nature - 17 Oct 1996

Moore J K, Haber J E

Abstract excerpt

Non-homologous repair of broken chromosomes in Saccharomyces cerevisiae can be studied at a defined location by expressing the site-specific HO endonuclease that cuts the mating-type (MAT) locus. When homologous recombination is prevented, most double-strand breaks are repaired by non-homologous...

Topics

Base Sequence
Chromosome Breakage
Chromosomes, Fungal
DNA Repair
DNA, Fungal
Deoxyribonucleases, Type II Site-Specific
Molecular Sequence Data
Mutation
RNA-Directed DNA Polymerase
Retroelements
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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