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Article

TIMELESS is an important mediator of CK2 effects on circadian clock function in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Sept 2008

Meissner Rose-Anne, Kilman Valerie L, Lin Jui-Ming, Allada Ravi

Abstract excerpt

Circadian oscillations in clock components are central to generation of self-sustained 24-h periodicity. In the Drosophila molecular clock, accumulation, phosphorylation, and degradation of PERIOD (PER) and TIMELESS (TIM) proteins govern period length. Yet little is known about the kinases that phosphorylate TIM in vivo. It has been shown previously that the protein kinase CK2 phosphorylates TIM in vitro. Here,...

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Source

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Identifiers

PMID: 18815259
DOI: 10.1523/JNEUROSCI.0840-08.2008
PMCID: PMC3032400

Genes

TIMELESS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TIMELESS is an important mediator of CK2 effects on circadian clock function in vivo.PMID 18815259Read ↗

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