Article
FCGR3B polymorphism in three ethnic Chinese populations.
Immunohematology - 1 Jan 2005
Yan L, Zhu F, Jin L, Lv Q, Fu Q
Abstract excerpt
Fc gamma RIIIb receptor is expressed primarily on neutrophils as three polymorphic antigens (HNA-1a, HNA-1b, and HNA-1c) that are encoded by alleles FCGR3B*1, FCGR3B*2, and FCGR3B*3, respectively. These antigens play an important role in immune neutropenia; their absence predisposes individuals who lack them to life-threatening infections. This study investigated the FCGR3B gene frequencies in three ethnic...
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