Isoimmune neonatal neutropenia caused by Fc gamma RIIIb antibodies in a Spanish child.

doi:10.1046/j.1537-2995.1995.35895357901.x

Back to search

Article

Isoimmune neonatal neutropenia caused by Fc gamma RIIIb antibodies in a Spanish child.

Transfusion - 1 Aug 1995

Puig N, de Haas M, Kleijer M, Montoro J A, Pérez A, Villalba J V, Gomez I, von dem Borne A E

Abstract excerpt

BACKGROUND: Fc gamma RIIIb deficiency is a rare defect in which neutrophils do not express Fc gamma RIIIb and therefore the individuals with this defect have an NA null phenotype. Soluble Fc gamma RIII in plasma is severely decreased and almost undetectable. During pregnancy, Fc gamma RIIIb defic...

Topics

Alleles
Chromosomes, Human, Pair 1
Female
Gene Deletion
Humans
Infant, Newborn
Infant, Newborn, Diseases
Isoantibodies
Male
Neutropenia
Pedigree
Receptors, IgG

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.