Article
Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import.
The Journal of cell biology - 1 Sept 1995
Corbett A H, Koepp D M, Schlenstedt G, Lee M S, Hopper A K, Silver P A
Abstract excerpt
The Saccharomyces cerevisiae gene, RNA1, encodes a protein with extensive homology to the mammalian Ran/TC4 GTPase activating protein. Using indirect immunofluorescence microscopy, we have demonstrated that rna1-1 mutant cells are defective in nuclear import of several proteins. The same result is obtained when nuclear import is examined in living cells using a nuclear protein fused to the naturally green...
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