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Article

Isolation of an extragenic suppressor of the rna1-1 mutation in Saccharomyces cerevisiae.

Molecular & general genetics : MGG - 1 Sept 1998

Hong S J, Yi Y S, Koh S S, Park O K, Kang H S

Abstract excerpt

The small GTPase Ran is essential for nucleocytoplasmic transport of macromolecules. In the yeast Saccharomyces cerevisiae, Rna1p functions as a Ran-GTPase activating protein (RanGAP1). Strains carrying the rna1-1 mutation exhibit defects in nuclear transport and, as a consequence, accumulate precursor tRNAs. We have isolated two recessive suppressors of the rna1-1 mutation. Further characterization of one of the...

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PMID: 9790597
DOI: 10.1007/s004380050830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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