Article
Talpid2 mutant chick limb has anteroposterior polarity and altered patterns of programmed cell death.
The Anatomical record - 1 Oct 1991
Dvorak L, Fallon J F
Abstract excerpt
The talpid2(ta2) chick mutant is of interest for the study of limb pattern formation. Talpid2 is a simple Mendelian recessive lethal mutation which affects the mesoderm and results in short, spade-like, polydactylous wings and legs. Here, we describe ta2 limb development with particular attention to those aspects of ta2 which may illuminate the process of normal limb development. From the onset of budding, ta2...
Topics
- Animals
- Cell Death
- Cell Differentiation
- Cell Polarity
- Chick Embryo
- Extremities
- Morphogenesis
- Mutation