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Article

Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development.

Developmental biology - 15 Oct 2002

Tümpel Stefan, Sanz-Ezquerro Juan J, Isaac Alison, Eblaghie Maxwell C, Dobson Julia, Tickle Cheryll

Abstract excerpt

Tbx3, a T-box gene family member related to the Drosophila gene optomotor blind (omb) and encoding a transcription factor, is expressed in anterior and posterior stripes in developing chick limb buds. Tbx3 haploinsufficiency has been linked with the human condition ulnar-mammary syndrome, in which predominantly posterior defects occur in the upper limb. Omb is expressed in Drosophila wing development in response...

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PMID: 12376101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development.PMID 12376101Read ↗

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