Streptozotocin-induced genotoxic effects in Chinese hamster cells: the resistant phenotype of V79 cells.

doi:10.1016/0165-7992(95)90074-8

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Article

Streptozotocin-induced genotoxic effects in Chinese hamster cells: the resistant phenotype of V79 cells.

Mutation research - 1 Jul 1995

Capucci M S, Hoffmann M E, Natarajan A T

Abstract excerpt

The genotoxic effects of the methylating agent streptozotocin (STZ) on Chinese hamster cells CHO-9 and V79 were evaluated. The induction of cell killing, chromosomal aberrations, sister-chromatid exchanges (SCEs) and mutations was analyzed. Comparisons were made with the the STZ aglyconic analogu...

Topics

Animals
Cell Line
Cell Survival
Chromosome Aberrations
Cricetinae
Cricetulus
Methylnitrosourea
Mutation
Phenotype
Sister Chromatid Exchange
Streptozocin

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