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Streptozotocin-induced genotoxic effects in Chinese hamster cells: the resistant phenotype of V79 cells.

Mutation research - 1 Jul 1995

Capucci M S, Hoffmann M E, Natarajan A T

Abstract excerpt

The genotoxic effects of the methylating agent streptozotocin (STZ) on Chinese hamster cells CHO-9 and V79 were evaluated. The induction of cell killing, chromosomal aberrations, sister-chromatid exchanges (SCEs) and mutations was analyzed. Comparisons were made with the the STZ aglyconic analogue N-methyl-N-nitrosourea (MNU). V79 cells were found to be more resistant than CHO-9 cells to STZ and MNU killing...

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Identifiers

PMID: 7651468
DOI: 10.1016/0165-7992(95)90074-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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