Assessment of antimutagenic effects of stobadine dihydrochloride on MNNG-induced mutations in Chinese hamster cells V79.

Article

Assessment of antimutagenic effects of stobadine dihydrochloride on MNNG-induced mutations in Chinese hamster cells V79.

Neoplasma - 1 Jan 1995

Horváthová E, Slamenová D, Chorvatovicová D, Wsólová L

Abstract excerpt

Mutagenicity of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and antimutagenic effect of antioxidant stobadine (STB) were investigated by so called HGPRT/V79 system. Cells were treated by STB before, during and after MNNG-treatment. Our results showed that the highest antimutagenic effect of STB w...

Topics

Animals
Antimutagenic Agents
Antioxidants
Carbolines
Cell Line
Cricetinae
Cricetulus
Methylnitronitrosoguanidine
Mutation

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