Article
Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome.
British journal of haematology - 1 Jul 1995
Ito E, Kasai M, Hayashi Y, Toki T, Arai K, Yokoyama S, Kato K, Tachibana N, Yamamoto M, Yokoyama M
Abstract excerpt
Acute megakaryoblastic leukaemia (M7) and transient myeloproliferative disorder in Down's syndrome (TMD) are characterized by rapid growth of abnormal blast cells which express megakaryocytic markers. To clarify properties of the blast cells in M7 and TMD cases, we examined erythroid markers expression in blasts from six cases with M7 and seven cases with TMD in this study. Erythroid-specific mRNAs encoding...
Topics
- 5-Aminolevulinate Synthetase
- Blotting, Northern
- Child
- Child, Preschool
- DNA-Binding Proteins
- Down Syndrome
- Erythrocytes
- Erythroid Precursor Cells
- Erythroid-Specific DNA-Binding Factors
- Female