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Article

Terminal differentiation in vitro of patient-derived post-TMD megakaryoblastic AML cells.

Annals of hematology - 1 Aug 2003

Classen C F, Gnekow A, Debatin K-M

Abstract excerpt

Differentiation induction is a therapeutic principle in acute promyelocytic leukemia (AML) using all- trans retinoic acid. In cell lines with properties of AML M6/M7 (K562 and CMK), differentiation towards megakaryopoietic and erythropoietic phenotypes can be induced in vitro. Transitory myeloproliferative disorder (TMD) is a self-limited disorder of newborn infants with Down syndrome, phenotypically resembling...

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Source

Identifiers

PMID: 12910377
DOI: 10.1007/s00277-003-0692-3

Genes

GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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