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Article

Transient abnormal myelopoiesis in non-Down syndrome neonate.

Pediatrics international : official journal of the Japan Pediatric Society - 1 Jan 2015

Ohkawa Teppei, Miyamoto Satoshi, Sugie Manabu, Tomizawa Daisuke, Imai Kohsuke, Nagasawa Masayuki, Morio Tomohiro, Mizutani Shuki, Takagi Masatoshi

Abstract excerpt

We encountered a case of neonatal acute megakaryoblastic leukemia not associated with Down syndrome (DS). Molecular cytogenetic analysis of leukemic blast cells indicated that increased blast cell status was caused by transient abnormal myelopoiesis with trisomy 21 and GATA1 mutation. Based on these molecular cytogenetic data, intensive chemotherapy was avoided, and the patient was successfully cured with...

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Identifiers

PMID: 25711269
DOI: 10.1111/ped.12500

Genes

GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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