Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Over-expression of EDAG in the myeloid cell line 32D: induction of GATA-1 expression and erythroid/megakaryocytic phenotype.

Journal of cellular biochemistry - 1 Jul 2010

Ding Ya-Li, Xu Cheng-Wang, Wang Zhi-Dong, Zhan Yi-Qun, Li Wei, Xu Wang-Xiang, Yu Miao, Ge Chang-Hui, Li Chang-Yan, Yang Xiao-Ming

Abstract excerpt

Erythroid differentiation-associated gene (EDAG), a hematopoietic tissue-specific transcription regulator, plays a key role in maintaining the homeostasis of hematopoietic lineage commitment. However, the mechanism and genes regulated by EDAG remain unknown. In this study, we showed that overexpression of EDAG in a myeloid cell line 32D led to an erythroid phenotype with increased number of benzidine-positive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Erythrocytes
Share to GATA1 Transcription Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Interleukin-3

Share to K562 Cells

Share to Megakaryocytes

Share to RNA Interference

Share to Up-Regulation

Source

Identifiers

PMID: 20564185
DOI: 10.1002/jcb.22597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Over-expression of EDAG in the myeloid cell line 32D: induction of GATA-1 expression and erythroid/megakaryocytic phenotype.PMID 20564185Read ↗

A HaemAtlas: characterizing gene expression in differentiated human blood cellsSemantic proximity Read ↗

Exome sequencing identifies highly recurrent somatic GATA2 and CEBPA mutations in acute erythroid leukemia.Semantic proximity Read ↗

[Expression of EDAG-1 gene in human leukemia and lymphoma cell lines].Semantic proximity Read ↗

Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generationSemantic proximity Read ↗

Regulatory association of long noncoding RNAs and chromatin accessibility facilitates erythroid differentiationSemantic proximity Read ↗

Expression of Transcription Factors during Megakaryocytic Differentiation of CD34+ Cells from Human Cord Blood Induced by ThrombopoietinSemantic proximity Read ↗

The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer.Semantic proximity Read ↗

Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiationSemantic proximity Read ↗

Gene Expression Profile of Megakaryocytes from Human Cord Blood CD34+ Cells Ex Vivo Expanded by ThrombopoietinSemantic proximity Read ↗

Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis.Semantic proximity Read ↗

Transcriptomic gene profiles in an ex vivo model of erythropoiesis to unravel molecular pathomechanisms of Sickle Cell DiseaseSemantic proximity Read ↗

Growth factor‐independent 1B gene (<i>GFI1B</i>) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.