Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CTL escape viral variants. II. Biologic activity in vivo.

Virology - 20 Aug 1995

Lewicki H A, Von Herrath M G, Evans C F, Whitton J L, Oldstone M B

Abstract excerpt

The proteins of lymphocytic choriomeningitis virus (LCMV) contain only three known peptide regions that are processed and then held in place by the MHC class I H-2b (Db) glycoprotein on the cell's surface for recognition by LCMV-specific Db-restricted cytotoxic T lymphocytes (CTL). These peptides are from the glycoprotein (GP), amino acids 33-41 KAVYNFATC (GP1) and 276-286 SGVENPGGYCL (GP2), and the nucleoprotein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Histocompatibility Antigens Class I
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Mice, Knockout

Share to Molecular Sequence Data

Share to Mutation

Share to Viral Proteins

Source

Identifiers

PMID: 7645248
DOI: 10.1006/viro.1995.1426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CTL escape viral variants. II. Biologic activity in vivo.PMID 7645248Read ↗

CTL escape viral variants. I. Generation and molecular characterization.Semantic proximity Read ↗

Discriminated selection among viral peptides with the appropriate anchor residues: implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection.Semantic proximity Read ↗

In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb.Semantic proximity Read ↗

The signal sequence of lymphocytic choriomeningitis virus contains an immunodominant cytotoxic T cell epitope that is restricted by both H-2D(b) and H-2K(b) molecules.Semantic proximity Read ↗

Viral escape from the neutralizing antibody response: the lymphocytic choriomeningitis virus model.Semantic proximity Read ↗

Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence.Semantic proximity Read ↗

In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes.Semantic proximity Read ↗

Functional management of an antiviral cytotoxic T-cell response.Semantic proximity Read ↗

Hierarchy among multiple H-2b-restricted cytotoxic T-lymphocyte epitopes within simian virus 40 T antigen.Semantic proximity Read ↗

Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes.Semantic proximity Read ↗

Impairment of CD4(+) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants.Semantic proximity Read ↗

T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.