Article
CTL escape viral variants. II. Biologic activity in vivo.
Virology - 20 Aug 1995
Lewicki H A, Von Herrath M G, Evans C F, Whitton J L, Oldstone M B
Abstract excerpt
The proteins of lymphocytic choriomeningitis virus (LCMV) contain only three known peptide regions that are processed and then held in place by the MHC class I H-2b (Db) glycoprotein on the cell's surface for recognition by LCMV-specific Db-restricted cytotoxic T lymphocytes (CTL). These peptides...
Topics
- Amino Acid Sequence
- Animals
- CD8-Positive T-Lymphocytes
- Histocompatibility Antigens Class I
- Killer Cells, Natural
- Lymphocytic choriomeningitis virus
- Mice
- Mice, Inbred Strains
- Mice, Knockout
- Molecular Sequence Data
- Mutation
- T-Lymphocytes, Cytotoxic
- Viral Proteins