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Article

Normal development and function of natural killer cells in CD3 epsilon delta 5/delta 5 mutant mice.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1995

Renard V, Ardouin L, Malissen M, Milon G, Lebastard M, Gillet A, Malissen B, Vivier E

Abstract excerpt

The CD3 epsilon polypeptide contributes to the cell surface display as well as to the signal transduction properties of the T-cell antigen receptor complex. Intriguingly, the distribution of CD3 epsilon is not restricted to T cells, since activated mouse, human, and avian natural killer (NK) cells do express intracytoplasmic CD3 epsilon polypeptides. CD3 epsilon is also present in the cytoplasm of fetal thymic...

Topics

Amino Acid Sequence
Animals
CD3 Complex
Cell Differentiation
Cytotoxicity, Immunologic
Female
Hematopoietic Stem Cells
Humans
In Vitro Techniques
Killer Cells, Natural

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Listeriosis

Male

Mice

Mice, Inbred C57BL

Mice, Mutant Strains

Molecular Sequence Data

Mutation

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 7638228
DOI: 10.1073/pnas.92.16.7545
PMCID: PMC41376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7638228-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Normal development and function of natural killer cells in CD3 epsilon delta 5/delta 5 mutant mice.PMID 7638228Read ↗

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