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Article

Protein kinase Cepsilon is dispensable for TCR/CD3-signaling.

Molecular immunology - 1 Feb 2005

Gruber Thomas, Thuille Nikolaus, Hermann-Kleiter Natascha, Leitges Michael, Baier Gottfried

Abstract excerpt

PKCepsilon has been strongly linked to cell activation and proliferation in many cell types, including leukemic T-cell lines. In particularly, an essential role of PKCepsilon has been established in the IKK-beta/I-kappaB/NF-kappaB transactivation cascade. To study the physiological function of PKCepsilon in primary T-cells, we used our newly established PKCepsilon null mice. Unexpectedly, however, we did not...

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Source

Identifiers

PMID: 15589318
DOI: 10.1016/j.molimm.2004.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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