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Article

Modulation of genetic resistance to hepatocarcinogenesis in DRH rats by partial hepatectomy.

Cancer letters - 30 Jun 2003

Liu Hongbo, Nobumoto Kazumi, Yamada Yoshihiro, Higashi Ken, Hiai Hiroshi

Abstract excerpt

The DRH is an inbred rat strain highly resistant to chemically induced hepatocarcinogenesis. Two clusters of resistance loci Drh1 and Drh2 on chromosome 1 and 4 yield strong resistance to the formation of enzyme-altered foci and their progression. To evaluate the effect of enhanced cell proliferation in the progression stage, a partial hepatectomy (PH) was carried out in (DRH x F344)F1 rats 8 weeks after the...

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Source

Identifiers

PMID: 12860283
DOI: 10.1016/s0304-3835(03)00187-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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