Article
Application of inter-simple sequence repeat PCR to mouse models: assessment of genetic alterations in carcinogenesis.
Genes, chromosomes & cancer - 1 Dec 2002
Benavides Fernando, Zamisch Mónica, Flores Mónica, Campbell Marcia R, Andrew Susan E, Angel Joe M, Licchesi Julien, Sternik Gabriel, Richie Ellen R, Conti Claudio J
Abstract excerpt
Genomic instability is believed to play a significant role in cancer development by facilitating tumor progression and tumor heterogeneity. Inter-simple sequence repeat (inter-SSR) PCR has been proved to be a fast and reproducible technique for quantitation of genomic instability (amplifications, deletions, translocations, and insertions) in human sporadic tumors. However, the use of inter-SSR PCR in animal...
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