Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure.

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Article

Mutations in the p53 gene in lung cancer are associated with cigarette smoking and asbestos exposure.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000

Wang X, Christiani D C, Wiencke J K, Fischbein M, Xu X, Cheng T J, Mark E, Wain J C, Kelsey K T

Abstract excerpt

It has been proposed that the patterns of mutations in the p53 tumor suppressor gene will provide clues to the mechanisms of cancer occurrence. Cigarette smoking is known to be the greatest risk factor for lung cancer. Epidemiological evidence has also implicated radon and asbestos as exposures t...

Topics

Aged
Asbestos
Female
Genes, p53
Humans
Lung Neoplasms
Male
Middle Aged
Mutation
Occupational Exposure
Risk Factors
Smoking

Source

Open in PubMed

Identifiers

PMID: 7549812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7549812-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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