Article
Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 1999
Gealy R, Zhang L, Siegfried J M, Luketich J D, Keohavong P
Abstract excerpt
Lung cancer incidence is increasing in women with little or no tobacco exposure, and the cause of this trend is not known. One possibility is increased sensitivity to environmental tobacco smoke in women nonsmokers diagnosed with lung cancer. To determine whether mutations associated with tobacco exposure are found in the lung tumors of women who are lifetime nonsmokers or occasional smokers, we compared the p53...
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