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Article

Molecular analysis of p53 and K-ras in lung carcinomas of coal miners.

International journal of molecular medicine - 1 Oct 2001

Sarkar F H, Li Y, Vallyathan V

Abstract excerpt

Thirty-three cases of non-small cell lung cancers (NSCLC) from the archives of National Coal Workers' Autopsy Study were studied for mutational alterations in p53 and K-ras using PCR-SSCP, DNA sequencing and PCR-oligonucleotide probe hybridization techniques. Mutations of the p53 were observed in 4 smokers (19%) and one in a never smoker (8%). Two polymorphisms in smokers were detected at codon 213, a common site...

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Identifiers

PMID: 11562787
DOI: 10.3892/ijmm.8.4.453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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